Name | Tetrahydrofurfuryl alcohol |
Synonyms | THFA 2-Oxolanemethanol Oxolane-2-methanol Tetrahydrofurfuryl a 2-Hydroxymethyl oxolane Tetrahydrofuryl Alcohol Tetrahydrofurfuryl alcohol Tetrahydrofuran-2-methanol Tetrahydro-2-furanmethanol Tetrahydrofurfruyl Alcohol tetrahydrofuran-2-ylmethanol TETRAHYDROFURFURYLIC ALCOHOL TETRAHYDROFURFURYL ALCOHOL FCC tetrahydro-2-furylmethanol tetrahydrofurfuryl alcohol |
CAS | 97-99-4 |
EINECS | 202-625-6 |
InChI | InChI=1/C5H10O2/c6-4-5-2-1-3-7-5/h5-6H,1-4H2 |
InChIKey | BSYVTEYKTMYBMK-UHFFFAOYSA-N |
Molecular Formula | C5H10O2 |
Molar Mass | 102.13 |
Density | 1.054 g/mL at 25 °C (lit.) |
Melting Point | -80 °C (lit.) |
Boling Point | 178 °C (lit.) |
Flash Point | 183°F |
JECFA Number | 1443 |
Water Solubility | soluble |
Solubility | acetone: miscible(lit.) |
Vapor Presure | 2.3 mm Hg ( 39 °C) |
Vapor Density | 3.52 (vs air) |
Appearance | Liquid |
Color | Clear |
Merck | 14,9213 |
BRN | 102723 |
pKa | 14.44±0.10(Predicted) |
Storage Condition | Store below +30°C. |
Sensitive | Hygroscopic |
Explosive Limit | 1.5-9.7%(V) |
Refractive Index | n20/D 1.452(lit.) |
Physical and Chemical Properties | Characteristics of colorless liquid, slightly odor. Hygroscopic. boiling point 177~178 ℃ relative density 1.0544 refractive index 1.4517 flash point 75 ℃ solubility, chloroform and benzene miscible, insoluble in paraffin. |
Use | Used as a solvent, also used as a raw material for the preparation of dihydrofuran, lysine, etc., and its esters are used as plasticizers |
Risk Codes | R36 - Irritating to the eyes R62 - Possible risk of impaired fertility R61 - May cause harm to the unborn child |
Safety Description | S39 - Wear eye / face protection. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
UN IDs | NA 1993 / PGIII |
WGK Germany | 2 |
RTECS | LU2450000 |
TSCA | Yes |
HS Code | 29321300 |
Toxicity | LD50 orally in Rabbit: 1600 mg/kg |
colorless liquid, slightly odorous. Hygroscopic. Flammable. Low toxicity. Miscible with water, ethanol, ether, acetone, chloroform and benzene, insoluble in paraffin. The relative density was 1. 0544. Boiling Point (look kPa) 177~178 °c. Refractive index 4517. Flash point 75 °c. Viscosity (25 °c) 5. 49MPA. s. Spontaneous ignition point 282.2.
prepared by one-step hydrogenation of furfural or two-step hydrogenation of furfural via furfuryl alcohol.
organic synthesis raw materials, can be prepared dihydrofuran, lysine, long-acting vitamin bi. Also used for the preparation of polyamide plastics, antifreeze, herbicides, pesticides. Their esters are used as plasticizers. Solvents for resins, paints and greases. Used as lubricant and dispersion in printing and dyeing industry
Drug. Also can be used as fatty acid Taro oil and some of the drug decolorization, deodorant.
FEMA | 3056 | TETRAHYDROFURFURYL ALCOHOL |
LogP | -0.14 at 24.7℃ |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
content analysis | measured by gas chromatography (GT-10-4) using a polar column method. |
toxicity | LD50 2500-4000mg/kg (rat). GRAS(FEMA). |
Use limit | is moderately limited (FDA,§ 172.515,2000). |
Use | is used as a solvent and also as a raw material for the preparation of dihydrofuran, lysine, etc, its esters are used as plasticizers GB 2760-1996 for the permitted use of flavorants. used in the preparation of succinic acid, pentanediol, Tetrahydrofuran, pyran, etc., also used as a solvent for coatings, resins and oils. In the printing and dyeing industry, it is used as a lubricant, a dispersant, a decolorizing agent for pharmaceuticals, a deodorizing agent, and a raw material for organic synthesis such as plasticizers, herbicides, and pesticides. Tetrahydrofuran methyl bromide was obtained by bromination of tetrahydrofurfuryl alcohol, and sodium thiosulfate was prepared by substitution of sodium thiosulfate. It is the raw material of long-acting vitamin B1 (furylthiamine). solvents for resins and oils. Oxidation of dyes and rubber. Manufacture of esters. Gelatin solution stabilizer. Wetting agent for printing and dyeing industry. Dispersant. Decolorizing deodorant for certain drugs. used as solvent, also used in rubber, Dye Industry |
production method | is obtained by hydrogenation of furfural. When a nickel-chromium-copper based catalyst is used, the reaction temperature is from 170 to 180 ° C. And the pressure is from 7.5 to 10.5MPa. The furfural is obtained by continuous pressure hydrogenation at 170-180 ° C. And 7.355-7.845MPa in the presence of catalyst Ni. |
category | flammable liquid |
toxicity grade | poisoning |
Acute toxicity | oral-rat LD50: 1600 mg/kg; Oral-mouse LD50: 2300 mg/kg |
stimulation data | eye-rabbit 20 mg/24 h moderate |
explosive hazard characteristics | explosive when mixed with air |
flammability hazard characteristics | flammable in open flame, high temperature, strong oxidant; combustion emissions |
storage and transportation characteristics | The package is complete, light, light; The warehouse is ventilated, away from open flame, high temperature, separate from oxidant |
fire extinguishing agent | foam, carbon dioxide, water mist, sand, dry powder |
spontaneous combustion temperature | 282°C |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |